Informed Health Choices Podcasts
Each episode includes a short story with an example of a treatment claim and a simple explanation of a Key Concept used to assess that claim
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Ebm@school – a curriculum of critical health literacy for secondary school students
A curriculum based on the concept of evidence-based medicine, which consists of six modules.
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Know Your Chances
This book has been shown in two randomized trials to improve peoples' understanding of risk in the context of health care choices.
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Dancing statistics: Explaining variance
A 5-minute film demonstrating the statistical concept of variance through dance.
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Dancing statistics: sampling & standard error
A 5-minute film demonstrating the statistical concept of sampling and standard error through dance.
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Calling Bullshit Syllabus
Carl Bergstrom's and Jevin West's nice syllabus for 'Calling Bullshit'.
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It’s just a phase
A resource explaining the differences between different trial phases.
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The Princess and the p-value
An interactive resource introducing reporting and interpretation of statistics in controlled trials.
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Explaining the mission of the AllTrials Campaign (TED talk)
Half the clinical trials of medicines we use haven’t been published. Síle Lane shows how the AllTrials Campaign is addressing this scandal.
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Building evidence into education
Ben Goldacre explains why appropriate infrastructure is need to do clinical trials of sufficient rigour and size to yield reliable results.
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The certainty of chance
Ben Goldacre reminds readers how associations may simply reflect the play of chance, and describes Deming’s illustration of this.
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The Man Who Swallowed The Pea, and Other Tall Tales
Tamara Ingamells’ lesson plan using the claim that MMR vaccination causes autism to help teenagers understand the importance of biases.
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Dragon Lesson Plan to investigate multivariate categorical data
Investigating multivariate data by sorting and organising a set of dragon cards to uncover information about the set.
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Critical appraisal
University of New South Wales Medical Statistics Tutorial 4 addresses Critical Appraisal.
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Probability and tests of statistical significance
University of New South Wales Medical Statistics Tutorial 6 addresses ‘Probability and tests of statistical significance’.
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A way to teach about systematic reviews
81 slides used by David Nunan (Centre for Evidence-Based Medicine, Oxford) to present ‘A way to teach about systematic reviews’.
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Detectives in the classroom
Five modules of materials for promoting epidemiology among high school students.
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Taking account of the play of chance
Differences in outcome events in treatment comparisons may reflect only the play of chance. Increased numbers of events reduces this problem
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Quantifying uncertainty in treatment comparisons
Small studies in which few outcome events occur are usually not informative and the results are sometimes seriously misleading.
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Critical appraisal of clinical trials
Slides developed by Amanda Burls for an interactive presentation covering the most important features of well controlled trials.
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How Science Works
Definitions of terms that students have to know for 'How Science Works' and associated coursework, ISAs, etc
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The Systematic Review
This blog explains what a systematic review is, the steps involved in carrying one out, and how the review should be structured.
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Making sense of results – CASP
This module introduces the key concepts required to make sense of statistical information presented in research papers.
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Avoiding biased selection from the available evidence
Systematic reviews are used to identify, evaluate and summarize all the evidence relevant to addressing a particular question.
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Preparing and maintaining systematic reviews of all the relevant evidence
Unbiased, up-to-date systematic reviews of all the relevant, reliable evidence are needed to inform practice and policy.
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Using the results of up-to-date systematic reviews of research
Trustworthy evidence from research is necessary, but not sufficient, to improve the quality of health care.
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Why comparisons must address genuine uncertainties
Too much research is done when there are no genuine uncertainties about treatment effects. This is unethical, unscientific, and wasteful.
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What are systematic reviews?
A 3-min video by Jack Nunn and The Cochrane Consumers and Communication group for people unfamiliar with the concept of systematic reviews.
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Goldilocks
Cartoon and blog about how poorly performed systematic reviews and meta-analyses may misrepresent the truth.
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Secret life of trials
The results of single comparisons of treatments can be misleading.
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Forest Plot Trilogy
Synthesising the results of similar but separate fair comparisons (meta-analysis) may help by yielding statistically more reliable estimates
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Introduction to clinical trials: lay-friendly video
This lay-friendly video introduction to clinical trials was created by the European Communication on Research Awareness Needs Project.
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Overview of study designs
11 slides and a 4-min commentary overviewing study designs for clinical research. (from Univ Mass Med School).
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Systematic Reviews
3 slides and a 4-min commentary about systematic reviews and meta-analyses (from Univ Mass Med School).
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Introduction to Critical Appraisal
30-slide introduction by Jason Curtis, to Critical Appraisal.
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Science Weekly Podcast – Ben Goldacre
A 1-hour audio interview with Ben Goldacre discussing misleading claims about research.
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Smart Health Choices: making sense of health advice
The Smart Health Choices e-book explains how to make informed health decisions.
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The basic principles of Evidence Based Medicine
A webpage explaining the foundations of systematic reviews.
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In defence of systematic reviews of small trials
An article discussing the strengths and weaknesses of systematic reviews of small trials.
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Evidence from Randomised Trials and Systematic Reviews
Dr Chris Cates' article discussing control of bias in randomised trials and explaining systematic reviews.
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Reducing the play of chance using meta-analysis
Combining data from similar studies (meta-analysis) can help to provide statistically more reliable estimates of treatment effects.
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Viva la Evidence!
A brilliant song and video by James McCormack explaining the basics of evidence-based medicine.
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What does the Cochrane logo tell us?
This video and animated slide presentation prepared by Steven Woloshin shows how the Cochrane logo was developed, and what it tells us.
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On taking a good look at ourselves
Iain Chalmers talks about failings in scientific research that lead to avoidable harm to patients and waste of resources.
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Breast cancer screening: well established but remains contentious
Since routine breast screening with mammography is well established in many countries one could well assume that mammographic screening must […]
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Aprotinin: effect on bleeding during and after surgery
Research funders, academic institutions, researchers, research ethics committees, and scientific journals are all complicit in unnecessary research. As we explained […]
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Respiratory distress in premature babies
Some research falls in between good and bad – it is plainly unnecessary. An example of such research concerns premature […]
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Why did you start?
‘Few principles are more fundamental to the scientific and ethical validity of clinical research than that studies should address questions […]
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Reports of new research should begin and end with systematic reviews
The report of a study [20] to assess the effects of giving steroids to people with acute traumatic brain injury […]
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Wasted resources in healthcare and research
Failure to do systematic reviews of relevant, reliable research evidence does harm even when it is not harming patients and […]
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Avoidable harm to patients
Recommended treatments for heart attacks that had appeared in textbooks published over a period of 30 years were compared with […]
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Reducing the play of chance in systematic reviews
Previously, we explained how the play of chance can be reduced by combining data from similar but separate studies – […]
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Identifying all the relevant evidence for systematic reviews
Identifying all the relevant evidence for systematic reviews – irrespective of the language or format of the relevant reports – […]
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Reducing biases in systematic reviews
Just as biases can distort individual tests of treatments and lead to false conclusions, so they can also distort reviews […]
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Systematic reviews of all the relevant, reliable evidence
Whilst it is easy to state that we should review the results of a particular alongside other relevant, reliable evidence, […]
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Is one study ever enough?
The simple answer is ‘hardly ever’. Very seldom will one fair treatment comparison yield sufficiently reliable evidence on which to […]
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Addressing uncertainties about the effects of treatments
Where do we go from here? Clinicians need to be able to draw on resources that provide the best current […]
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Bone marrow transplantation
However, the demise of mutilating surgery did not spell the end of the ‘more is better’ mindset – far from […]
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Evening primrose oil for eczema
Even if inadequately assessed treatments do not kill or harm, they can waste money. Eczema is a distressing skin complaint […]
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